Cosyntropin (acetate)

Cosyntropin is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) residues 1-24. It increases the plasma concentration of hydrocortisone (Cay-20739) in mares more rapidly and consistently than natural ACTH 1-24. Formulations containing cosyntropin have been used to diagnose adrenal deficiencies in humans, dogs, and horses.Formal Name: alpha1-24-corticotropin, acetate. CAS Number: 60189-34-6. Synonyms: ACTH (1-24), Adrenocorticotropic Hormone 1-24, Tetracosactide. Molecular Formula: C136H210N40O31S . XC2H4O2. Formula Weight: 2993.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: [H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@H](C(N3CCC[C@H]3C(O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CNC6=C5C=CC=C6)=O)=O)CC7=CC=CC=C7)=O)CC8=CN=CN8)=O)=O)CCSC)=O)=O)CC9=CC=C(O)C=C9)=O.CC(O)=O. InChi Code: InChI=1S/C136H210N40O31S.C2H4O2/c1-75(2)109(127(200)154-71-106(181)156-88(31-13-17-52-137)114(187)158-89(32-14-18-53-138)115(188)159-91(35-21-56-149-134(142)143)116(189)164-96(37-23-58-151-136(146)147)131(204)175-60-25-39-104(175)126(199)173-111(77(5)6)128(201)163-90(33-15-19-54-139)120(193)171-110(76(3)4)129(202)169-101(65-80-43-47-84(180)48-44-80)132(205)176-61-26-40-105(176)133(206)207)172-125(198)103-38-24-59-174(103)130(203)95(34-16-20-55-140)157-107(182)70-153-113(186)99(66-81-68-152-87-30. InChi Key: XDSGCNRPXJYVQS-GLMYKROOSA-N.