AOD-9604 (acetate)

AOD-9604 is a synthetic lipolytic 15-amino acid peptide fragment derived from human growth hormone. In vivo, AOD-9604 (250 µg/kg per day) decreases body weight, epididymal adipose tissue mass, and brown adipose tissue weight in ob/ob mice. It also enhances cartilage regeneration in a rabbit model of collagenase-induced knee osteoarthritis.Formal Name: cyclic (7->14)-disulfide, L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamylglycyl-L-seryl-L-cysteinylglycyl-L-phenylalanine, acetate. Molecular Formula: C78H123N23O23S2 . XC2H4O2. Formula Weight: 1815.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble. SMILES: OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]2C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CSSC2)C(NCC(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)=O)CO)=O)=O)CCC(O)=O)=O)C(C)C)=O)CO)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O.CC(O)=O. InChi Code: InChI=1S/C78H123N23O23S2.C2H4O2/c1-9-41(8)62(101-68(115)47(18-14-28-86-78(83)84)91-69(116)50(29-38(2)3)95-63(110)45(79)30-43-19-21-44(104)22-20-43)75(122)100-61(40(6)7)74(121)94-49(23-25-56(80)105)67(114)98-55-37-126-125-36-54(65(112)88-32-57(106)89-51(76(123)124)31-42-15-11-10-12-16-42)97-70(117)52(34-102)90-58(107)33-87-64(111)48(24-26-59(108)109)93-73(120)60(39(4)5)99-71(118)53(35-103)96-66(113)46(92-72(55)119)17-13-27-85-77(81)82,1-2(3)4/h10-12,15-16,19-22,38-41,45-55,60-62,102-104H,9,13-14,17-18,23-37,79H2,1-8H3,(H2,80,105)(H,87,111)(H,88,112)(H,89,106)(H,90,107)(H,91,116)(H,92,119)(H,93,120)(H,94,121)(H,95,110)(H,96,113)(H,97,117)(H,98,114)(H,99,118)(H,100,122)(H,101,115)(H,108,109)(H,123,124)(H4,81,82,85)(H4,83,84,86),1H3,(H,3,4)/t41-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,60+,61-,62-,/m0./s1. InChi Key: UABQRJZABFFQRR-UPOQWEFCSA-N.