AIP-II

Description: AIP-II is a macrocyclic peptide signaling molecule produced by Staphylococcus aureus for quorum sensing. It binds to the AgrC-II receptor, regulating the expression of virulence genes within Staphylococcus aureus. Additionally, AIP-II acts as an antagonist to the AgrC-I receptor. Target: Antibacterial. Smiles: C([C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)[C@H](C)C)=O)CC(N)=O)=O)C)=O)CSC1=O)C2=CC=CC=C2