Enalaprilat-d5

Enalaprilat-d5 is intended for use as an internal standard for the quantification of enalaprilat (Cay-17603) by GC- or LC-MS. Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 5.8 nM) and an active metabolite of the prodrug enalapril (Cay-16041). It reduces the pressor response induced by angiotensin I in hypertensive rats when administered at a dose of 10 mg/kg.. SMILES: OC([C@@H](N[C@@H](C)C(N1CCC[C@H]1C(O)=O)=O)CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O. InChi Code: InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1/i2D,3D,4D,6D,7D. InChi Key: LZFZMUMEGBBDTC-HJJZLVALSA-N