Zu "K01283" wurden 283 Artikel gefunden!
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Anti-ACE / Angiotensin I Converting Enzyme
Artikelnummer: NSJ-FY13058
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. ACE antibody detects Angiotensin I converting enzyme, a zinc-dependent peptidase that plays a pivotal role in blood pressure regulation and electrolyte balance. The UniProt recommended name is Angiotensin I converting enzyme (ACE). This...
| Schlagworte: | Anti-ACE, Anti-Kininase II, Anti-Angiotensin-converting enzyme, Anti-Dipeptidyl carboxypeptidase I, ACE Antibody /... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Human ACE ELISA Kit
Artikelnummer: ARG80958.96
Protein function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane...
| Schlagworte: | Anti-DCP, Anti-ACE, EC=3.2.1.-, EC=3.4.15.1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
2.053,00 €
COVID-19 Forschung
Captopril
Artikelnummer: Cay15313-1
Captopril is an inhibitor of angiotensin-converting enzyme (ACE, IC50 = 23 nM for the rabbit lung enzyme). It inhibits contractions in isolated guinea pig ileal segments induced by angiotensin I or bradykinin (IC50s = 23 and 3 nM, respectively) but not those induced by angiotensin II, histamine, acetylcholine,...
| Schlagworte: | SA 333, SQ 14,225, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-L-proline |
| Anwendung: | ACE inhibitor |
| CAS | 62571-86-2 |
| MW: | 217.3 D |
ab 54,00 €
Zofenopril-d5
Artikelnummer: Cay43425-1
Zofenopril-d5 is intended for use as an internal standard for the quantification of zofenopril (Cay-29525) by GC- or LC-MS. Zofenopril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor zofenoprilat (Cay-38124). Zofenopril is hydrolyzed by cardiac esterases in vivo to form zofenoprilat. It...
| Schlagworte: | (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-((phenyl-d5)thio)-L-proline |
| Anwendung: | GC-MS, LC-MS, internal standard, ACE inhibitor |
| MW: | 434.58 D |
518,00 €
Ramiprilat
Artikelnummer: Cay15557-1
Ramiprilat is the active metabolite of ramipril (Cay-15558) and functions as an angiotensin-converting enzyme inhibitor (pKi = 9.08 in human heart) to suppress the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, thereby preventing vasoconstriction. Furthermore, ramiprilat is reported...
| Schlagworte: | Ramipril Diacid,... |
| Anwendung: | ACE inhibitor |
| CAS | 87269-97-4 |
| MW: | 388.5 D |
ab 93,00 €
COVID-19 Forschung
Lisinopril
Artikelnummer: Cay16833-100
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.2 nM). It reduces the formation of endothelin-1 (Cay-24127) and increases nitric oxide (NO) in human vascular endothelial cells when used at a concentration of 0.1 nM. Lisinopril inhibits the pressor response to angiotensin I in anesthetized...
| Schlagworte: | MK-521, MK-522, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline |
| Anwendung: | ACE inhibitor |
| CAS | 76547-98-3 |
| MW: | 405.5 D |
ab 18,00 €
Ramipril
Artikelnummer: Cay15558-100
Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Cay-15557). Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis....
| Schlagworte: | HOE 498,... |
| Anwendung: | Angiotensin-converting enzyme (ACE) inhibitor |
| CAS | 87333-19-5 |
| MW: | 416.5 D |
ab 93,00 €
Enalapril (maleate)
Artikelnummer: Cay16041-500
Enalapril is an inhibitor of angiotensin-converting enzyme (ACE, IC50 = 1.2 nM in porcine plasma). In vivo, enalapril (0.05-1 mg/kg, p.o.) inhibits pressor responses induced by angiotensin I (Cay-24737) in rats and dogs in a dose-dependent manner. Enalapril reduces heart rate, systolic and diastolic blood pressures,...
| Schlagworte: | N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline, 2Z-butenedioate |
| Anwendung: | Angiotensin-converting enzyme (ACE) inhibitor |
| CAS | 76095-16-4 |
| MW: | 492.5 D |
ab 57,00 €
Enalapril
Artikelnummer: LKT-E5202.1
An antihypertensive agent known to reduce the incidence of vascular dementia and Alzheimer's disease. Found to have a potential for colon cancer prevention. (ACE inhibitor)
| Schlagworte: | N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline |
| Anwendung: | ACE inhibitor |
| CAS | 75847-73-3 |
| MW: | 376,45 D |
ab 585,00 €
Fosinopril (sodium salt)
Artikelnummer: Cay21899-10
Fosinopril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril (2.5 mg/kg) reduces...
| Schlagworte: | SQ 28,555, 4S-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline,... |
| Anwendung: | Angiotensin-converting enzyme inhibitor |
| CAS | 88889-14-9 |
| MW: | 585.6 D |
ab 56,00 €
Enalaprilat (hydrate)
Artikelnummer: Cay17603-50
Enalaprilat is an active metabolite of the angiotensin-converting enzyme (ACE) inhibitor enalapril (Cay-16041).. Enalaprilat is esterified with ethanol to produce enalapril in order to enable oral activity and subsequently metabolized in vivo to the active form by various esterases. Enalaprilat is reported to...
| Schlagworte: | N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline, dihydrate |
| Anwendung: | Enalapril metabolite |
| CAS | 84680-54-6 |
| MW: | 384.4 D |
ab 67,00 €
Perindopril
Artikelnummer: Cay20796-100
Perindopril is an orally active angiotensin converting enzyme (ACE) inhibitor that effectively lowers blood pressure. It is a prodrug that is metabolized to perindoprilat (Cay-17574), a specific, competitive inhibitor of ACE (IC50 = 1.5-3.2 nM in vitro).Formal Name:...
| Schlagworte: | (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid |
| Anwendung: | ACE inhibitor |
| CAS | 82834-16-0 |
| MW: | 368.5 D |
ab 102,00 €