Flunisolide

Flunisolide is a fluorinated corticosteroid receptor agonist that induces reversible pyloric hyalinization in CD-1 mice following oral administration at a dose of 200 µg/kg per day. Formulations containing flunisolide have been used for the treatment of asthma.Formal Name: 6alpha-fluoro-11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione. CAS Number: 3385-03-3. Synonyms: RS 3999. Molecular Formula: C24H31FO6. Formula Weight: 434.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:2): 0.2 mg/ml. lambdamax: 238 nm. SMILES: O=C1C=C[C@@]2(C)C([C@@H](F)C[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@]5([H])[C@@]4(C(CO)=O)OC(C)(C)O5)=C1. InChi Code: InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1. InChi Key: XSFJVAJPIHIPKU-XWCQMRHXSA-N.