3-O-methyl Estradiol

3-O-methyl Estradiol is a synthetic estrogen. It disrupts microtubule networks in V79 Chinese hamster cells (EC50 = 9 µM) and inhibits the proliferation of the same cells by 92% when used at a concentration of 20 µM. 3-O-methyl Estradiol (25 mg in a 0. ml solution, p.o.) decreases serum cholesterol levels and increases body weight loss, indicating feminizing activity, in male rats fed a high-cholesterol diet. It has been used as a standard for the quantification of 17beta-estradiol in hen urine.. Solulibility: DMSO: Soluble: =10 mg/ml: Ethanol: Soluble: =10 mg/ml.