STING-IN-3

Description: STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. Target: STING. Smiles: CCCCCCc1ccc(NC(=O)c2ccc(o2)[N+]([O-])=O)cc1. References: Simone M Haag , Muhammet F Gulen , Luc Reymond et al. Targeting STING with covalent small-molecule inhibitors[J]. Nature, 2018.