Sodium dichloroacetate

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T3604-50mg	50 mg	7 - 10 Werktage*	31,00 €
TGM-T3604-100mg	100 mg	7 - 10 Werktage*	45,00 €
TGM-T3604-1mL	1 ml	7 - 10 Werktage*	49,00 €
TGM-T3604-200mg	200 mg	7 - 10 Werktage*	58,00 €

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Description: Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase... mehr

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Produktinformationen "Sodium dichloroacetate"

Description: Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 µM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth. Target: Dehydrogenase, Apoptosis, Reactive Oxygen Species, PDK. Smiles: C(C(=O)[O-])(Cl)Cl.[Na+]. References: Bonnet S, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007 Jan,11(1):37-51.

Schlagworte:	Sodium Dichloroacetate, BCA, bichloroacetic acid, DCA, Sodium dichloroacetate (DCA)
Hersteller:	TargetMol
Hersteller-Nr:	T3604

Eigenschaften

Anwendung:	Targets pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (PDK2_3_4)
MW:	150.92 D
Formel:	C2HCl2NaO2

Datenbank Information

CAS :	2156-56-1\| Passende Produkte
KEGG ID :	K00898 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H315, H319, H335, H351
P-Sätze:	P201, P202, P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P308+P313, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501