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Sodium dichloroacetate
Artikelnummer: TGM-T3604-100mg
Description: Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 µM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth. Target:...
| Schlagworte: | Sodium Dichloroacetate, BCA, bichloroacetic acid, DCA, Sodium dichloroacetate (DCA) |
| Anwendung: | Targets pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (PDK2_3_4) |
| CAS | 2156-56-1 |
| MW: | 150.92 D |
ab 31,00 €
Sodium dichloroacetate
Artikelnummer: AG-CR1-3684-G001
Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor, consequently activating pyruvate dehydrogenase (PDH). Decreases glycolysis. Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Antitumor agent. Decreases tumor growth in vitro and in vivo. Induces...
| Schlagworte: | Dichloroacetic acid sodium salt, Bichloroacetic acid, BCA |
| Anwendung: | PDK inhibitor |
| CAS | 2156-56-1 |
| MW: | 140.9 D |
50,00 €
