Zu "K00898" wurden 122 Artikel gefunden!
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VER-246608
Artikelnummer: BPS-82820-1
VER-246608 is a potent and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50s of 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively.1
| Schlagworte: | PDK inhibitor, pyruvate dehydrogenase kinase inhibitor, |
| Anwendung: | PDK (pyruvate dehydrogenase kinase) inhibitor |
| CAS | 1684386-71-7 |
| MW: | 552,96 D |
ab 485,00 €
PDK3 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02470-100ug
Description: PDK3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is Q922H2.
| Schlagworte: | Pdk3, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3 |
| MW: | 30.3 kD |
ab 281,00 €
PDK4 Protein, Mouse, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04445-50ug
Description: Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an...
| Schlagworte: | AV005916, pyruvate dehydrogenase kinase 4 |
| MW: | 74.4 kD |
497,00 €
Leelamine hydrochloride
Artikelnummer: TGM-T11834-2mg
Description: Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabinoid receptor type 1 (CB1) agonist and suppresses SREBP1-regulated fatty acid/lipid...
| Anwendung: | PDK inhibitor |
| CAS | 16496-99-4 |
| MW: | 321.93 D |
98,00 €
VER-246608
Artikelnummer: TGM-T17224-100mg
Description: VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively).VER-246608 disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Consistent with a PDK...
| Anwendung: | PDK1/2/3/4 inhibitor |
| CAS | 1684386-71-7 |
| MW: | 552.96 D |
ab 48,00 €
Sodium dichloroacetate
Artikelnummer: TGM-T3604-100mg
Description: Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 µM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth. Target:...
| Schlagworte: | Sodium Dichloroacetate, BCA, bichloroacetic acid, DCA, Sodium dichloroacetate (DCA) |
| Anwendung: | Targets pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (PDK2_3_4) |
| CAS | 2156-56-1 |
| MW: | 150.92 D |
ab 31,00 €
CAY10703
Artikelnummer: TGM-T37355-10mg
Description: Dichloroacetate (DCA) is an inhibitor of all pyruvate dehydrogenase kinase (PDHK) isoforms, which are enzymes that phosphorylate and inhibit PDH in mitochondria. Inhibition of PDHK shifts cell metabolism from glycolysis to mitochondrial glucose oxidation, an effect that has relevance to cancer, type 2...
| Anwendung: | PDHK inhibitor |
| CAS | 1841421-67-7 |
| MW: | 479.01 D |
ab 77,00 €
Anti-PDK2
Artikelnummer: CSB-PA003732.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PDK2, Anti-PDKII, Anti-PDHK2, EC=2.7.11.2, Anti-PDH kinase 2, Anti-Pyruvate dehydrogenase kinase isoform 2,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-PDK4
Artikelnummer: CSB-PA052803.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PDK4. Antigen Species: Human
| Schlagworte: | Anti-PDK4, Anti-PDHK4, EC=2.7.11.2, Anti-Pyruvate dehydrogenase kinase isoform 4, Anti-[Pyruvate dehydrogenase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-PDK2
Artikelnummer: CSB-PA266329.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PDK2. Antigen Species: Human
| Schlagworte: | Anti-PDK2, Anti-PDKII, Anti-PDHK2, EC=2.7.11.2, Anti-PDH kinase 2, Anti-Pyruvate dehydrogenase kinase isoform 2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-PDK2
Artikelnummer: CSB-PA574849.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-PDK2, Anti-PDKII, Anti-PDHK2, EC=2.7.11.2, Anti-PDH kinase 2, Anti-Pyruvate dehydrogenase kinase isoform 2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
283,00 €
Anti-PDK4
Artikelnummer: CSB-PA642637.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PDK4. Antigen Species: Human
| Schlagworte: | Anti-PDK4, Anti-PDHK4, EC=2.7.11.2, Anti-Pyruvate dehydrogenase kinase isoform 4, Anti-[Pyruvate dehydrogenase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €