SB-633825

SB-633825 is a multi-kinase inhibitor. It inhibits tunica internal endothelial kinase 2 (Tie2), serine/threonine kinase 10 (STK10), and breast tumor kinase (BRK, IC50s = 3.5, 66, and 150 nM, respectively). InChI: InChI=1S/C28H25N3O3S/c1-18-15-24(35(4,32)33)9-10-25(18)28-30-26(19-11-13-29-14-12-19)27(31(28)2)22-6-5-21-17-23(34-3)8-7-20(21)16-22/h5-17H,1-4H3 InChIKey: ZDSNJSQTPLXCSG-UHFFFAOYSA-N SMILES: O=S(C1=CC=C(C2=NC(C3=CC=NC=C3)=C(N2C)C4=CC5=C(C=C(C=C5)OC)C=C4)C(C)=C1)(C)=O