Zu "K05121" wurden 111 Artikel gefunden!
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BAY-826
Artikelnummer: Cay41365-1
BAY-826 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2, IC50 = 0.5 nM). It inhibits Tie2 autophosphorylation in human umbilical vein endothelial cells (HUVECs, EC50 = 1.3 nM). BAY-826 (0.1 or 1 µM), in combination with radiation, reduces colony formation in a colony formation assay using SMA-497,...
| Schlagworte: | BAY-Tie2, BAY-Tunica Interna Endothelial Cell Kinase 2,... |
| Anwendung: | Tie2 inhibitor |
| CAS | 1448316-08-2 |
| MW: | 558.5 D |
ab 47,00 €
Human TIE2 / TEK ELISA Kit
Artikelnummer: ARG83031.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has...
| Schlagworte: | TEK, TIE2, hTIE2, hTIE2, CD202b, CD202b, p140 TEK, p140 TEK, Angiopoietin-1 receptor, Angiopoietin-1 receptor, Endothelial... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
638,00 €
Anti-Phospho-TEK (Y992)
Artikelnummer: CSB-PA006341.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-TEK, Anti-phospho-TIE2, Anti-phospho-hTIE2, Anti-phospho-CD202b, Anti-phospho-p140 TEK, EC=2.7.10.1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Anti-TEK
Artikelnummer: CSB-PA041300.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TEK. Antigen Species: Human
| Schlagworte: | Anti-TEK, Anti-TIE2, Anti-hTIE2, Anti-CD202b, Anti-p140 TEK, EC=2.7.10.1, Anti-Angiopoietin-1 receptor, Anti-Endothelial... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-TEK
Artikelnummer: CSB-PA982820.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TEK. Antigen Species: Human
| Schlagworte: | Anti-TEK, Anti-TIE2, Anti-hTIE2, Anti-CD202b, Anti-p140 TEK, EC=2.7.10.1, Anti-Angiopoietin-1 receptor, Anti-Endothelial... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-TIE2 / TEK
Artikelnummer: NSJ-RQ5554
0.5mg/ml if reconstituted with 0.2ml sterile DI water. TIE2, also known as TEK tyrosine kinase, is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three...
| Schlagworte: | Anti-hTIE2, Anti-CD202b, Anti-p140 TEK, Anti-Angiopoietin-1 receptor, Anti-Endothelial tyrosine kinase,... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Mouse Tie2 (TEK Tyrosine Kinase, Endothelial) ELISA Kit
Artikelnummer: ELK-ELK1306.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Tie2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Tie2. Next,...
| Schlagworte: | Hyk, HYK, Tek, STK1, mTIE2, CD202b, p140 TEK, EC=2.7.10.1, Angiopoietin-1 receptor, Endothelial tyrosine kinase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 303,00 €
Anti-TIE2
Artikelnummer: NSJ-F50680-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are...
| Schlagworte: | Anti-TEK, Anti-TIE2, Anti-hTIE2, Anti-CD202b, Anti-p140 TEK, EC=2.7.10.1, Anti-Angiopoietin-1 receptor, Anti-Endothelial... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
RK-20448
Artikelnummer: Cay25606-5
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 µM, respectively). It also inhibits BLK, Csk, Fyn, and Lyn (IC50s = 0.37, 4.27, 2.03, and 0.43 µM, respectively). RK-20448 is the cis isomer of A-419259 (Cay-18168).Formal Name:...
| Schlagworte: | 7-[cis-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Anwendung: | ATP-competitive Lck / Src / VEGF2R / Tie-2 inhibitor |
| CAS | 479501-40-1 |
| MW: | 482.6 D |
ab 60,00 €
Pexmetinib
Artikelnummer: Cay26187-10
Pexmetinib is a dual inhibitor of Tie2 and p38 MAPK (IC50s = 1, 26, and 35 nM for Tie2, p38alpha, and p38beta, respectively). It also inhibits Abl, ARG, FGFR, FLT1, FLT4, Fyn, HCK, LYN, and MINK (IC50s = 4, 10, 28, 47, 42, 41, 26, 25, and 26 nM, respectively). Pexmetinib (0.5 and 1 µM) reduces proliferation of KG-1...
| Schlagworte: | ARRY 614,... |
| Anwendung: | Tie2 inhibitor, p38 MAPK inhibitor |
| CAS | 945614-12-0 |
| MW: | 556.6 D |
ab 50,00 €
Anti-TIE-2 (human), clone tek2
Artikelnummer: AG-20T-0102-C100
Native human TIE-2 in ELISA experiments and on the surface of different human cell types. Lyophilized. TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin...
| Schlagworte: | Anti-TEK, Anti-TIE2, Anti-VMCM, Anti-hTIE2, Anti-VMCM1, Anti-CD202b, EC=2.7.10.1, Anti-p140 TEK, Anti-Angiopoietin-1... |
| Anwendung: | ELISA, FC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
429,00 €
Anti-TIE-2 (human), clone tek9
Artikelnummer: AG-20T-0103-C100
Native human TIE-2 in ELISA experiments and on the surface of different human cell types. Lyophilized. TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin...
| Schlagworte: | Anti-TEK, Anti-TIE2, Anti-VMCM, Anti-hTIE2, Anti-VMCM1, Anti-CD202b, EC=2.7.10.1, Anti-p140 TEK, Anti-Angiopoietin-1... |
| Anwendung: | ELISA, FC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
429,00 €