MBCQ

MBCQ is an inhibitor of phosphodiesterase 5 (PDE5, IC50 = 19 nM). It is selective for PDE5 over PDE1, PDE2, PDE3, and PDE4 (IC50s = >100 µM for all). It induces relaxation of isolated porcine coronary arteries precontracted with prostaglandin F2alpha (PGF2alpha, EC50 = 190 nM).Formal Name: N-(1,3-benzodioxol-5-ylmethyl)-6-chloro-4-quinazolinamine. CAS Number: 150450-53-6. Molecular Formula: C16H12ClN3O2. Formula Weight: 313.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml. lambdamax: 294, 326, 339 nm. SMILES: ClC1=CC2=C(C=C1)N=CN=C2NCC3=CC(OCO4)=C4C=C3. InChi Code: InChI=1S/C16H12ClN3O2/c17-11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20). InChi Key: CNODHOSDWZLJGA-UHFFFAOYSA-N.