Lofepramine

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T15773-2mg	2 mg	7 - 10 Werktage*	42,00 €
TGM-T15773-5mg	5 mg	7 - 10 Werktage*	65,00 €
TGM-T15773-1mL	1 ml	7 - 10 Werktage*	72,00 €
TGM-T15773-10mg	10 mg	7 - 10 Werktage*	91,00 €
TGM-T15773-25mg	25 mg	7 - 10 Werktage*	187,00 €
TGM-T15773-50mg	50 mg	7 - 10 Werktage*	280,00 €
TGM-T15773-100mg	100 mg	7 - 10 Werktage*	420,00 €

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Description: Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively... mehr

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Produktinformationen "Lofepramine"

Description: Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors. Target: 5-HT Receptor, Norepinephrine. Smiles: C(CCN(CC(=O)C1=CC=C(Cl)C=C1)C)N2C=3C(CCC=4C2=CC=CC4)=CC=CC3. References: Lancaster SG, et al. Lofepramine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1989 Feb,37(2):123-40.

Schlagworte:	Lopramine, Amplit, Leo 640, Gamanil
Hersteller:	TargetMol
Hersteller-Nr:	T15773

Eigenschaften

Anwendung:	Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT)
MW:	418.96 D
Formel:	C26H27ClN2O

Datenbank Information

CAS :	23047-25-8\| Passende Produkte
KEGG ID :	K05035 \| Passende Produkte
Protein Atlas Nr. :	Neuropharmacologics/Ion Channel Modulators

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H336, H370, H373
P-Sätze:	P260, P261, P264, P270, P271, P312, P314, P321, P304+P340, P308+P311, P405, P403+P233, P501