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Lofepramine
Artikelnummer: TGM-T15773-100mg
Description: Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors....
| Schlagworte: | Lopramine, Amplit, Leo 640, Gamanil |
| Anwendung: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 23047-25-8 |
| MW: | 418.96 D |
ab 42,00 €
Lofepramine
Artikelnummer: Cay20813-1
Lofepramine is a first generation tricyclic antidepressant that is extensively metabolized to desipramine. It potently inhibits serotonin and norepinephrine transporters (Kds = 70 and 5.4 nM, respectively) and less potently antagonizes serotonin, histamine, and muscarinic receptors.Formal Name:...
| Schlagworte: | Lopramine, 1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-ethanone |
| Anwendung: | Antidepressant, serotonin-noradrenaline reuptake inhibitor (SNRI) |
| CAS | 23047-25-8 |
| MW: | 419 D |
ab 44,00 €
