Irinotecan

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T6228-10mg	10 mg	7 - 10 Werktage*	30,00 €
TGM-T6228-25mg	25 mg	7 - 10 Werktage*	42,00 €
TGM-T6228-1mL	1 ml	7 - 10 Werktage*	49,00 €
TGM-T6228-50mg	50 mg	7 - 10 Werktage*	58,00 €
TGM-T6228-100mg	100 mg	7 - 10 Werktage*	88,00 €
TGM-T6228-200mg	200 mg	7 - 10 Werktage*	126,00 €
TGM-T6228-500mg	500 mg	7 - 10 Werktage*	228,00 €

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Description: Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA... mehr

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Produktinformationen "Irinotecan"

Description: Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death. Target: Topoisomerase, Autophagy. Smiles: CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12. References: Keyvani-Ghamsari S, et al. Effect of irinotecan on HMGB1, MMP9 expression, cell cycle, and cell growth in breast cancer (MCF-7) cells. Tumour Biol. 2017 Apr,39(4):1010428317698354.

Schlagworte:	CPT-11, Topotecin, (+)-Irinotecan
Hersteller:	TargetMol
Hersteller-Nr:	T6228

Eigenschaften

Anwendung:	Targets DNA topoisomerase I [EC:5.6.2.1] (TOP1)
MW:	586.68 D
Formel:	C33H38N4O6

Datenbank Information

CAS :	97682-44-5\| Passende Produkte
KEGG ID :	K03163 \| Passende Produkte
Protein Atlas Nr. :	Apoptosis, Cell Cycle, DNA Repair

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H302, H315, H318, H361, H373
P-Sätze:	P201, P202, P260, P264, P270, P280, P314, P321, P330, P301+P310, P302+P352, P305+P351+P338, P308+P313, P332+P313, P362+P364, P405, P501