Compound 56

Compound 56 is a highly potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR, IC50 = 0.006 nM). It has been used to inhibit EGFR activity in pancreatic cancer cell lines and to induce the differentiation of rat mesenchymal stem cells.Formal Name: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine. CAS Number: 171745-13-4. Molecular Formula: C18H18BrN3O2. Formula Weight: 388.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 2 mg/ml, DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml, Ethanol: 2 mg/ml. lambdamax: 208, 230, 252, 333 nm. SMILES: BrC1=CC(NC2=NC=NC3=C2C=C(OCC)C(OCC)=C3)=CC=C1. InChi Code: InChI=1S/C18H18BrN3O2/c1-3-23-16-9-14-15(10-17(16)24-4-2)20-11-21-18(14)22-13-7-5-6-12(19)8-13/h5-11H,3-4H2,1-2H3,(H,20,21,22). InChi Key: YXOXHAUUTIOBDA-UHFFFAOYSA-N.