Zu "K04361" wurden 974 Artikel gefunden!
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Erlotinib
Artikelnummer: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Schlagworte: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
ab 51,00 €
NEU
Anti-EGF Receptor / EGFR, clone 688CT33.1.3
Artikelnummer: NSJ-F40405-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding...
| Schlagworte: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-EGF Receptor / EGFR, clone 51CT78.40.5
Artikelnummer: NSJ-F40415-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding...
| Schlagworte: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | IHC, FC, WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-EGF Receptor / EGFR
Artikelnummer: NSJ-F50597-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely...
| Schlagworte: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Tyr998)
Artikelnummer: NSJ-F48503-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Tyr1016)
Artikelnummer: NSJ-F48552-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Tyr1172)
Artikelnummer: NSJ-F48508-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | WB, DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-EGF Receptor / EGFR
Artikelnummer: NSJ-F50598-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely...
| Schlagworte: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Tyr1069)
Artikelnummer: NSJ-F48475-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | WB, DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Ser768)
Artikelnummer: NSJ-F48553-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-phospho-EGF Receptor / EGFR (Ser1070)
Artikelnummer: NSJ-F48516-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
MTX-211
Artikelnummer: Cay45142-1
MTX-211 is a dual inhibitor of PI3Kalpha and EGFR (IC50s = <100 nM for both). It reduces viability of 5637, EJ, and UM-UC-3 bladder cancer cells (IC50s = 1.075, 1.514, and 2.189 µM, respectively), an effect that can be partially inhibited by glutathione (GSH). MTX-211 also induces apoptosis, increases the levels of...
| Schlagworte: | N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]-methanesulfonamide |
| Anwendung: | PI3Kalpha/EGFR dual inhibitor |
| CAS | 1952236-05-3 |
| MW: | 478.32 D |
ab 55,00 €