Cardamonin

Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity. It has been shown to suppress nitric oxide and prostaglandin E2 synthesis, to suppress cyclooxygenase-2 expression, and to inhibit NF-kappaB signaling. It can also target the Bcl-2 protein, inducing apoptosis in cancer cells.Formal Name: (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one. CAS Number: 19309-14-9. Synonyms: Alpinetin chalcone, Cardamomin. Molecular Formula: C16H14O4. Formula Weight: 270.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml, Ethanol: 1 mg/ml. lambdamax: 343 nm. SMILES: OC1=C(C(/C=C/C2=CC=CC=C2)=O)C(OC)=CC(O)=C1. InChi Code: InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+. InChi Key: NYSZJNUIVUBQMM-BQYQJAHWSA-N.