Zu "K11987" wurden 309 Artikel gefunden!
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COX-2 (human) Inhibitor Screening Assay Kit
Artikelnummer: Cay701080-96
The COX-2 (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride (SnCl2) reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2alpha. This assay includes recombinant human COX-2 and is an excellent...
| Schlagworte: | Cyclooxygenase 2 |
| Anwendung: | Inhibitor screening |
584,00 €
COX Fluorescent Inhibitor Screening Assay Kit
Artikelnummer: Cay700100-192
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme exhibiting both COX and peroxidase activities. The COX component converts arachidonic acid to a hydroperoxy endoperoxide (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol (PGH2), the...
| Schlagworte: | Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit |
| Anwendung: | COX inhibitor screening |
895,00 €
Anti-COX-2 (Clone CX229)
Artikelnummer: Cay160112-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) to the hydroperoxy endoperoxide...
| Schlagworte: | Cyclooxygenase 2, PGHS-2, Prostaglandin H Synthase 2 |
| Anwendung: | IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, ovine, monkey |
422,00 €
NEU
Meloxicam
Artikelnummer: Cay40657-10
Meloxicam (Cay-40657) is an analytical reference standard categorized as a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor. Meloxicam has been found as an adulterant in illicit samples distributed as food in capsule form. Formulations containing meloxicam have been used in the treatment of...
| Schlagworte: | UH-AC 62XX, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide |
| Anwendung: | Analytical reference standard, NSAID, COX-2 inhibitor |
| CAS | 71125-38-7 |
| MW: | 351.4 D |
ab 66,00 €
Loxoprofen-SRS
Artikelnummer: Cay38122-1
Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen (Cay-35088). Intravenous administration of loxoprofen-SRS inhibits acetic acid-induced writhing, reduces...
| Schlagworte: | 4-[[(1R,2S)-2-hydroxycyclopentyl]methyl]-alphaS-methyl-benzeneacetic acid |
| Anwendung: | NSAID, COX inhibitor, active loxoprofen metabolite |
| CAS | 83648-76-4 |
| MW: | 248.3 D |
ab 34,00 €
4-Biphenylacetic Acid
Artikelnummer: Cay38116-25
4-Biphenylacetic acid is a non-steroidal anti-inflammatory drug (NSAID) and an active metabolite of the prodrug fenbufen (Cay-28851). It inhibits prostaglandin E2 (PGE2, Cay-14010) synthesis in a cell-free assay (IC50 = 3.2 µM). In vivo, 4-biphenylacetic acid (2 mg/kg) suppresses UV-induced erythema in guinea pigs....
| Schlagworte: | p-Biphenylacetic Acid, Cl-83544, Felbinac, LY601017, NSC 16284, [1,1'-biphenyl]-4-acetic acid |
| Anwendung: | NSAID, active fenbufen metabolite |
| CAS | 5728-52-9 |
| MW: | 212.2 D |
ab 47,00 €
Benzydamine (hydrochloride)
Artikelnummer: Cay39808-25
Benzydamine is a non-steroidal anti-inflammatory drug (NSAID). It decreases the viability of THP-1 monocytes, Saos-2 osteosarcoma, and HGF-1 gingival cancer cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively). Benzydamine (10 µg/ml) reduces LPS-induced increases in the levels of IL-6 and TNF-alpha secreted...
| Schlagworte: | N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride |
| Anwendung: | NSAID, COX inhibitor |
| CAS | 132-69-4 |
| MW: | 345.9 D |
ab 39,00 €
NS 398
Artikelnummer: Cay70590-5
NS 398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.Formal Name: N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide. CAS Number: 123653-11-2....
| Schlagworte: | N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 123653-11-2 |
| MW: | 314.4 D |
ab 65,00 €
Celecoxib
Artikelnummer: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Anwendung: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
ab 156,00 €
(+)-Naproxen (sodium salt)
Artikelnummer: Cay37554-25
(+)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor. It inhibits COX-1 and COX-2 in COS-1 cells expressing the human enzymes (IC50s = 4.8 and 28.4 µM, respectively). (+)-Naproxen inhibits thromboxane B2 (TXB2, Cay-19030) and prostaglandin E2 (PGE2, Cay-14010) production ex vivo in...
| Schlagworte: | (S)-Naproxen, CG 3117, (alphaS)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid, monosodium salt |
| Anwendung: | NSAID, COX inhibitor |
| CAS | 26159-34-2 |
| MW: | 252.2 D |
ab 81,00 €
Rat PTGS2/COX-2 (Prostaglandin Endoperoxide Synthase 2)...
Artikelnummer: ELK-ELK2681.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PTGS2/COX-2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat...
| Schlagworte: | Ptgs2, COX-2, Cox-2, PGHS-2, PHS II, EC=1.14.99.1, PGH synthase 2, Cyclooxygenase-2, Prostaglandin H2 synthase 2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human PTGS2/COX-2 (Prostaglandin Endoperoxide Synthase 2)...
Artikelnummer: ELK-ELK2096.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PTGS2/COX-2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human...
| Schlagworte: | COX-2, PGHS-2, PHS II, PGH synthase 2, Cyclooxygenase-2, Prostaglandin H2 synthase 2, Prostaglandin G/H synthase 2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €