Zu "K11987" wurden 327 Artikel gefunden!
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COX Fluorescent Inhibitor Screening Assay Kit
Artikelnummer: Cay700100-192
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme exhibiting both COX and peroxidase activities. The COX component converts arachidonic acid to a hydroperoxy endoperoxide (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol (PGH2), the...
| Schlagworte: | Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit |
| Anwendung: | COX inhibitor screening |
915,00 €
COX-2 (human) Inhibitor Screening Assay Kit
Artikelnummer: Cay701080-96
The COX-2 (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride (SnCl2) reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2alpha. This assay includes recombinant human COX-2 and is an excellent...
| Schlagworte: | Cyclooxygenase 2 |
| Anwendung: | Inhibitor screening |
597,00 €
Anti-COX-2 (Clone CX229)
Artikelnummer: Cay160112-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) to the hydroperoxy endoperoxide...
| Schlagworte: | Cyclooxygenase 2, PGHS-2, Prostaglandin H Synthase 2 |
| Anwendung: | IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, ovine, monkey |
431,00 €
NS 398
Artikelnummer: Cay70590-5
NS 398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.Formal Name: N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide. CAS Number: 123653-11-2....
| Schlagworte: | N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 123653-11-2 |
| MW: | 314.4 D |
ab 66,00 €
Celecoxib
Artikelnummer: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Anwendung: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
ab 164,00 €
Fenclofenac
Artikelnummer: Cay41709-1
Fenclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 7 and 4 µM for COX-1 and COX-2, respectively). It reduces paw volume in a rat model of adjuvant-induced polyarthritis when administered at doses of 3, 15, and 75 mg/kg and reverses yeast-induced motor impairments, a measure of...
| Schlagworte: | RX-67408, 2-(2,4-dichlorophenoxy)-benzeneacetic acid |
| Anwendung: | NSAID, COX inhibitor |
| CAS | 34645-84-6 |
| MW: | 297.1 D |
ab 35,00 €
COX-2 (human, recombinant)
Artikelnummer: Cay60122-5
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Schlagworte: | PHS II, PGHS-2, PHS II, PGHS-2, PGH synthase 2, PGH synthase 2, Prostaglandin H2 synthase 2, Prostaglandin H2 synthase 2,... |
| Anwendung: | Enzyme activity |
1.123,00 €
Anti-COX-2 (mouse) (aa 584-598)
Artikelnummer: Cay160126-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Schlagworte: | Anti-Cox-2, Anti-COX-2, Anti-PES-2, Anti-COX-2, Anti-PES-2, Anti-PHS II, Anti-PGHS-2, Anti-PHS II, Anti-PGHS-2,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | murine, rat, human, ovine |
431,00 €
Loxoprofenol-SRS
Artikelnummer: TGM-T72669-100mg
Description: Loxoprofenol-SRS, a new intravenous non-steroidal anti-inflammatory drug (NSAID) and the active metabolite of Loxoprofen, demonstrates significantly enhanced anti-inflammatory and analgesic (pain-relieving) effects. Target: Others. Smiles: C(C1=CC=C([C@@H](C(O)=O)C)C=C1)[C@@H]2[C@@H](O)CCC2
| Anwendung: | NSAID, COX inhibitor, active loxoprofen metabolite |
| CAS | 83648-76-4 |
| MW: | 248.32 D |
ab 1.520,00 €
FK 3311
Artikelnummer: TGM-T7207-100mg
Description: FK 3311 (COX-2 Inhibitor V) is an orally available, cell-permeable sulfonanilide that functions as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID). Target: COX. Smiles: CC(=O)c1ccc(NS(C)(=O)=O)c(Oc2ccc(F)cc2F)c1. References: Oshima K , Yabata Y , Yoshinari D , et al. The Effects of...
| Schlagworte: | COX-2 Inhibitor V, FK-3311 |
| Anwendung: | Cox-2 inhibitor |
| CAS | 116686-15-8 |
| MW: | 341.33 D |
ab 40,00 €
Flufenamic Acid-d4
Artikelnummer: TGM-T71303-1mg
Description: Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, NSAID, COX inhibitor |
| CAS | 1185071-99-1 |
| MW: | 285.26 D |
ab 394,00 €
APHS
Artikelnummer: TGM-T69926-10mg
Description: APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1. Target: Others. Smiles: S(CC#CCCCC)C1=C(OC(C)=O)C=CC=C1
| Anwendung: | Potent COX-1 / COX-2 inhibitor |
| CAS | 209125-28-0 |
| MW: | 262.37 D |
ab 30,00 €