Zu "K11987" wurden 353 Artikel gefunden!
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COX Fluorescent Inhibitor Screening Assay Kit
Artikelnummer: Cay700100-192
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme exhibiting both COX and peroxidase activities. The COX component converts arachidonic acid to a hydroperoxy endoperoxide (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol (PGH2), the...
| Schlagworte: | Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit |
| Anwendung: | COX inhibitor screening |
1.031,00 €
COX-2 (human) Inhibitor Screening Assay Kit
Artikelnummer: Cay701080-96
The COX-2 (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride (SnCl2) reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2alpha. This assay includes recombinant human COX-2 and is an excellent...
| Schlagworte: | Cyclooxygenase 2 |
| Anwendung: | Inhibitor screening |
740,00 €
COX-2 (human, recombinant) COX-FIS Assay Reagent
Artikelnummer: Cay700104-1
| Schlagworte: | COX2, PTGS2, COX-2, PHS II, PGHS-2, EC=1.14.99.1, PGH synthase 2, Cyclooxygenase-2, Prostaglandin H2 synthase 2,... |
| Anwendung: | Kit component |
371,00 €
Anti-COX-2 (Clone CX229)
Artikelnummer: Cay160112-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) to the hydroperoxy endoperoxide...
| Schlagworte: | Cyclooxygenase 2, PGHS-2, Prostaglandin H Synthase 2 |
| Anwendung: | IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, ovine, monkey |
468,00 €
Anti-Recombinant COX2, clone 6C10
Artikelnummer: E-AN301043L.100
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue...
| Schlagworte: | Anti-PTGS2, Anti-PHS II, Anti-Cyclooxygenase-2, Anti-Prostaglandin H2 synthase 2, Anti-Prostaglandin G/H synthase 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Cyclooxygenase 2 / COX-2 / PTGS2
Artikelnummer: NSJ-RQ8793
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. [UniProt]
| Schlagworte: | Anti-PTGS2, Anti-PHS II, Anti-Cyclooxygenase-2, Anti-Prostaglandin H2 synthase 2, Anti-Prostaglandin G/H synthase 2,... |
| Anwendung: | WB, IHC (paraffin), FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
NS 398
Artikelnummer: Cay70590-5
NS 398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.Formal Name: N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide. CAS Number: 123653-11-2....
| Schlagworte: | N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 123653-11-2 |
| MW: | 314.4 D |
ab 75,00 €
Celecoxib
Artikelnummer: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Anwendung: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
ab 164,00 €
COX-2 (human, recombinant)
Artikelnummer: Cay60122-5
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Schlagworte: | PHS II, PGHS-2, PHS II, PGHS-2, PGH synthase 2, PGH synthase 2, Prostaglandin H2 synthase 2, Prostaglandin H2 synthase 2,... |
| Anwendung: | Enzyme activity |
1.224,00 €
(±)-Ibuprofen
Artikelnummer: Cay70280-5
An NSAID and non-selective COX inhibitor (IC50s = 2.6 and 1.3 µM for human recombinant COX-1 and COX-2, respectively), inhibits late-phase formalin-induced paw licking in mice (ED50 = 6.1 mg/kg), inhibits acetic acid-induced writhing in mice (ED50 = 0.47 mg/kg). Formulation: A crystalline solid. InChI:...
| Schlagworte: | DL-Ibuprofen, NSC 256857, U-18753, (±)-a-methyl-4-(2-methylpropyl)-benzeneacetic acid |
| Anwendung: | NSAID, non-selective COX inhibitor |
| CAS | 15687-27-1 |
| MW: | 206.3 D |
ab 23,00 €
Anti-COX-2 (mouse) (aa 584-598)
Artikelnummer: Cay160126-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Schlagworte: | Anti-Cox-2, Anti-COX-2, Anti-PES-2, Anti-COX-2, Anti-PES-2, Anti-PHS II, Anti-PGHS-2, Anti-PHS II, Anti-PGHS-2,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | murine, rat, human, ovine |
468,00 €
CAY10404
Artikelnummer: Cay70210-1
CAY10404 is an inhibitor of COX-2 (IC50 = 50 = >500 µM). CAY10404 inhibits the proliferation of SH-EP and SH-SY5Y neuroblastoma cells (IC50s = ~60 µM for both), and induces apoptosis and cell cycle arrest at the G2/M phase in the same cells. It inhibits carrageenan-induced paw edema in rats when administered at a...
| Schlagworte: | 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole |
| Anwendung: | COX-2 inhibitor |
| CAS | 340267-36-9 |
| MW: | 367.4 D |
ab 36,00 €