Bupranolol

Bupranolol is an antagonist of beta-adrenergic receptors (beta-ARs, Kis = 6-15 nM for beta1- and beta2-ARs). In vivo, bupranolol (10 µmol/kg) reduces heart rate and diastolic blood pressure in pithed rats.Formal Name: 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol. CAS Number: 14556-46-8. Synonyms: (±)-Bupranolol. Molecular Formula: C14H22ClNO2. Formula Weight: 271.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml. SMILES: ClC1=CC=C(C)C=C1OCC(CNC(C)(C)C)O. InChi Code: InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3. InChi Key: HQIRNZOQPUAHHV-UHFFFAOYSA-N.