BI-187004

BI-187004 is an inhibitor of 11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1, IC50 = 31 nM).Formal Name: (4aR,9aS)-1-(1H-benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile. CAS Number: 1303515-32-3. Molecular Formula: C21H18N4O. Formula Weight: 342.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: O=C(C1=CC=C2C(NC=N2)=C1)N3[C@]4([H])[C@@](CCC3)([H])C5=CC(C#N)=CC=C5C4. InChi Code: InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1. InChi Key: VVZNCSHIBODHMZ-UZLBHIALSA-N.