Zu "K15680" wurden 73 Artikel gefunden!
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INCB 13739
Artikelnummer: Cay40223-10
INCB 13739 is an inhibitor of 11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1, IC50 = 3.2 nM). It is greater than 1,000-fold selective for 11beta-HSD1 over 11beta-HSD2, the mineralocorticoid receptor, and the glucocorticoid receptor at 5 µM. INCB 13739 inhibits 11beta-HSD1 activity in peripheral blood mononuclear...
| Schlagworte: | (3S)-1-[(3-chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-3-piperidinecarboxamide |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 872506-67-7 |
| MW: | 398.9 D |
ab 112,00 €
Carbenoxolone (sodium salt)
Artikelnummer: Cay18240-1
Carbenoxolone is a derivative of beta-glycyrrhetinic acid (Cay-11845), a major metabolite of glycyrrhizin, one of the main constituents of licorice. Similar to beta-glycyrrhetinic acid and glycyrrhizin, carbenoxolone has been shown to exhibit anti-ulcerative and anti-inflammatory properties. Carbenoxolone inhibits...
| Schlagworte: | (3beta,20beta)-3-(3-carboxy-1-oxopropoxy)-11-oxo-olean-12-en-29-oic acid, disodium salt |
| Anwendung: | Hydroxysteroid (11-beta) dehydrogenase 1 inhibitor |
| CAS | 7421-40-1 |
| MW: | 614.7 D |
ab 57,00 €
Carbenoxolone
Artikelnummer: LKT-C0167.1
A synthetic derivative of glycyrrhetinic acid
| CAS | 5697-56-3 |
| MW: | 570.76 D |
ab 53,00 €
BVT 2733
Artikelnummer: Cay22203-5
BVT 2733 is an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1, Cay-10007815). In a mouse model of hyperglycemia and hyperinsulinemia, BVT 2733 (100 mg/kg) inhibits 11beta-HSD1 activity in isolated liver and decreases blood glucose and insulin concentrations. It decreases the expression of...
| Schlagworte: | 3-chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]-benzenesulfonamide |
| Anwendung: | 11-beta-HSD1 inhibitor |
| CAS | 376640-41-4 |
| MW: | 429 D |
ab 134,00 €
Anti-HSD11B1 / HDL, C-terminal
Artikelnummer: ARG63708.100
Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol. [The UniProt...
| Schlagworte: | Anti-HSD11, Anti-11-DH, Anti-HSD11B1, Anti-11-beta-HSD1, EC=1.1.1.146, Anti-11-beta-hydroxysteroid dehydrogenase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Human HSD11B1 ELISA Kit
Artikelnummer: G-HUFI01853.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-HSD11B1
Artikelnummer: NSJ-R30441
0.5mg/ml if reconstituted with 0.2ml sterile DI water. 11-beta-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that...
| Schlagworte: | Anti-HSD11, Anti-11-DH, Anti-11-beta-HSD1, Anti-7-oxosteroid reductase, Anti-11-beta-hydroxysteroid dehydrogenase 1,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
790,00 €
Anti-HSD11B1
Artikelnummer: NSJ-R33358-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 11-beta-hydroxysteroid dehydrogenase 1 Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:10497248). Catalyzes reversibly the...
| Schlagworte: | Anti-HSD11, Anti-11-DH, Anti-11-beta-HSD1, Anti-11-beta-hydroxysteroid dehydrogenase 1, Anti-Corticosteroid... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-Hsd11b1
Artikelnummer: NSJ-R36132-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Hydroxysteroid (11-beta) dehydrogenase 1 Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. [The UniProt Consortium]
| Schlagworte: | Anti-11-DH, Anti-Hsd11, Anti-Hsd11b1, Anti-11-beta-HSD1, Anti-11beta-HSD1A, EC=1.1.1.146, Anti-11-beta-hydroxysteroid... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
836,00 €
Anti-HSD11B1
Artikelnummer: E-AB-52192.120
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a...
| Schlagworte: | Anti-11-DH, Anti-HSD11, Anti-HSD11B1, Anti-11-beta-HSD1, EC=1.1.1.146, Anti-11-beta-hydroxysteroid dehydrogenase 1,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-HSD11B1L
Artikelnummer: G-PACO37334.50
HSD11B1L Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC applications. HSD11B1L Antibody is a high quality polyclonal antibody for research use only.
| Schlagworte: | Anti-HSD3, Anti-11-DH3, Anti-HSD11B1L, EC=1.1.1.-, Anti-11-beta-HSD3, Anti-Short-chain dehydrogenase/reductase 10,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
313,00 €
Anti-HSD11B1
Artikelnummer: ATA-HPA047729.100
Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:10497248). Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to...
| Schlagworte: | Anti-11-DH, Anti-HSD11, Anti-11-beta-HSD1, Anti-11-beta-hydroxysteroid dehydrogenase 1, Anti-Corticosteroid... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €