BGC-20-1531 hydrochloride(1186532-61-5 free base)

Description: BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine. Target: Prostaglandin Receptor. Smiles: CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(O2)C)COC3=CC=C(C=C3)C4=NC=C(C=C4)OC.Cl. References: Czigler A , Toth L , Szarka N , et al. Prostaglandin E2, a postulated mediator of neurovascular coupling, at low concentrations dilates whereas at higher concentrations constricts human cerebral parenchymal arterioles[J]. Prostaglandins & other lipid mediators, 2019, 146:106389.