1-BCP

1-BCP is a positive allosteric modulator of AMPA receptors. 1-BCP (1 mM) selectively increases the release of norepinephrine induced by AMPA, but not NMDA or kainic acid, in rat hippocampal slices. It increases the amplitude and duration of primed field excitatory postsynaptic potentials (EPSPs) in rat hippocampal slices (EC50s = 480 and 590 µM, respectively). 1-BCP enhances memory in two-odor discrimination and radial maze tests, as well as in the Morris water maze, in rats when administered at a dose of 120 mg/kg.Formal Name: 1,3-benzodioxol-5-yl-1-piperidinyl-methanone. CAS Number: 34023-62-6. Molecular Formula: C13H15NO3. Formula Weight: 233.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 30 mg/ml. SMILES: O=C(N1CCCCC1)C2=CC=C3OCOC3=C2. InChi Code: InChI=1S/C13H15NO3/c15-13(14-6-2-1-3-7-14)10-4-5-11-12(8-10)17-9-16-11/h4-5,8H,1-3,6-7,9H2. InChi Key: BXBNADAPIHHXJQ-UHFFFAOYSA-N.