Zu "K05200" wurden 55 Artikel gefunden!
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Cyclothiazide
Artikelnummer: Cay16335-50
Receptors for AMPA are ionotropic glutamate receptors with critical roles in neurological development and function. Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM). It blocks the rapid agonist-induced...
| Schlagworte: | Doburil, 1,1-dioxide 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide |
| Anwendung: | AMPA receptor potentiator |
| CAS | 2259-96-3 |
| MW: | 389.9 D |
ab 67,00 €
Anti-GRIA4, Internal
Artikelnummer: ARG64711.100
Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory...
| Schlagworte: | Anti-GluA4, Anti-GRIA4, Anti-GluR4, Anti-GLUR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-GLUR4 (Glutamate Receptor 4)
Artikelnummer: NSJ-R31620
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These...
| Schlagworte: | Anti-GRIA4, Anti-GLUR4, Anti-GluA4, Anti-GluR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-GRIA4
Artikelnummer: NSJ-R34495-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Glutamate receptor, ionotrophic, AMPA 4, GLUR4, GLURD Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important...
| Schlagworte: | Anti-GRIA4, Anti-GLUR4, Anti-GluA4, Anti-GluR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Tianeptine (sodium salt)
Artikelnummer: Cay17561-500
Tianeptine is an atypical antidepressant. It is an agonist of the µ-opioid receptor (MOR, EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also has effects on the glutamate system. Tianeptine (30 mg/kg) decreases immobility in the forced swim test in...
| Schlagworte: | 7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-heptanoic acid, monosodium salt |
| Anwendung: | Glutamate receptor / AMPA receptor modulator |
| CAS | 30123-17-2 |
| MW: | 458.9 D |
ab 49,00 €
S18986
Artikelnummer: Cay14937-5
S18986 is a positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that potently enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S18986 is orally bioavailable and penetrates the blood-brain barrier in animals....
| Schlagworte: | 2,3,3aS,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine, 5,5-dioxide |
| Anwendung: | Glutamate ionotropic receptor positive allosteric modulator |
| CAS | 175340-20-2 |
| MW: | 224.3 D |
ab 49,00 €
CX-516
Artikelnummer: Cay14936-50
CX-516 is an AMPA receptor modulator. It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner....
| Schlagworte: | Ampalex, BDP-12, Benzoyl-Piperidine-12, 1-piperidinyl-6-quinoxalinyl-methanone |
| Anwendung: | AMPA modulator |
| CAS | 154235-83-3 |
| MW: | 241.3 D |
ab 75,00 €
Talampanel
Artikelnummer: Cay15341-5
Talampanel is an allosteric AMPA receptor antagonist (IC50 = 2.5 µM in cerebellar Purkinje neurons using voltage-clamp electrophysiology). It reduces the firing rate of spinal neurons in rats by 68% when administered at a dose of 10 mg/kg following AMPA administration. It is protective against seizures in mouse...
| Schlagworte: | GYKI 53773, LY 300164, (8R)-7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
| Anwendung: | Allosteric AMPA receptor antagonist |
| CAS | 161832-65-1 |
| MW: | 337.4 D |
ab 146,00 €
Anti-GluR4
Artikelnummer: ARG58874.100
Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory...
| Schlagworte: | Anti-GluA4, Anti-GLUR4, Anti-GluR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective glutamate... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
LY404187
Artikelnummer: Cay28741-50
LY404187 is a benzothiadiazide positive allosteric modulator of AMPA receptors. It increases glutamate-induced activation of GluR1i, -2i, -2o, -3i, and -4i subunit-containing AMPA receptors with EC50 values of 5.65, 0.15, 1.44, 1.66, and 0.21 µM, respectively, in a calcium influx assay. LY404187 is selective for...
| Schlagworte: | N-[2-(4'-cyano[1,1'-biphenyl]-4-yl)propyl]-2-propanesulfonamide |
| Anwendung: | AMPA receptor positive allosteric modulator |
| CAS | 211311-95-4 |
| MW: | 342.5 D |
ab 163,00 €
Anti-GRIA4
Artikelnummer: E-AB-52035.120
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of...
| Schlagworte: | Anti-GluA4, Anti-GluR4, Anti-GLUR4, Anti-GluR-4, Anti-GluR-D, Anti-Glutamate receptor 4, Anti-AMPA-selective glutamate... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-GRIA4
Artikelnummer: E-AB-53406.120
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of...
| Schlagworte: | Anti-GluA4, Anti-GluR4, Anti-GLUR4, Anti-GluR-4, Anti-GluR-D, Anti-Glutamate receptor 4, Anti-AMPA-selective glutamate... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €