Proprotein Convertase 9, Mouse, BioAssay(TM) DuoSet ELISA Development Kit (FH3, HCHOLA3, NARC-1, PC9

This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing. Sample Type: Cell culture supernates, Intended Use: This BioAssay(TM) DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse Proprotein Convertase 9 (PCSK9). DuoSets are designed for the analysis of cell culture supernates. Range: ~31.2-2000pg/ml, Specificity: This DuoSet recognizes 60kD, 53kD, and LDL R complexed recombinant mouse PCSK9. Kit Components: PCSK9 capture antibody, 1x vial, PCSK9 detection antibody, 1x vial, Recombinant mouse PCSK9 standard, 1x 3vials, Streptavidin-HRP, 1x vial, Storage and Stability: Store other components at 4°C. Stable for 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.