Anti-phospho-Synapsin I, (Ser9) (Synapsin 1, Synapsin-1, SYN1, SYN-1, Synapsin-I, SYNI, SYN-I, Brain

Synapsin is a neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is thought to function in the regulation of neurotransmitter release. Synapsin exists as a homodimer and at the subcellular level is located at the cell junction and synapse. It interacts with CAPON and forms a ternary complex with NOS1. Synapsin is a substrate of at least four different protein kinases and it is likely that phosphorylation plays a role in its regulation in the nerve terminal. Defects in SYN1 cause X-linked recessive epilepsy associated with variable learning disabilities and behavior disorders. Applications: Suitable for use in Western Blot. Other applications not tested. , Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.