Anti-phospho-c-Myb (Thr486)

Anti-phospho-c-Myb (Thr486)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-C47 100 µg - -

6 - 10 Werktage*

684,00 €
 
This affinity-purified antibody is directed against the phosphorylated form of mouse c-Myb... mehr
Produktinformationen "Anti-phospho-c-Myb (Thr486)"
This affinity-purified antibody is directed against the phosphorylated form of mouse c-Myb protein at the pT486 residue. Antiserum was first purified against the phosphorylated form of the immunizing peptide.  The resultant affinity purified antibody was then cross adsorbed against the non-phosphorylated form of the immunizing peptide.  Reactivity occurs against mouse c-Myb pT486 protein and the antibody is specific for the phosphorylated form of the protein.  This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells. Reactivity with non-phosphorylated mouse c-Myb is minimal by ELISA and western blot. A BLAST analysis was used to suggest reactivity with c-Myb from mouse based on a 100% homology with the immunizing sequence.  Expect reactivity with c-Myb from rat, pig, human, horse, platypus, opossum, orangutan, spider monkey, bonobo, gorilla, and chimpanzee, with a v-myb myeloblastosis viral oncogene homolog, all isoforms (also avian version) from human, and with a protooncogene c-myb, and a v-myb myeloblastosis viral oncogene homolog (avian), both from cattle, all based on a 93% homology with the immunizing sequence.  Cross-reactivity with c-Myb from other sources has not been determined. Protein function: Transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. [The UniProt Consortium]
Schlagworte: Anti-phospho-Myb, Anti-phospho-Proto-oncogene c-Myb, Anti-phospho-Transcriptional activator Myb
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-C47

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: mouse
Immunogen: synthetic peptide corresponding to an internal region of mouse c-Myb protein surrounding amino acid residue 486.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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