FluoSite Anti-CDH6 Antibody, PE Labeled

This anti-CDH6 (Cadherin-6, also known as K-cadherin) antibody is a purified monoclonal recombinant antibody, which is labeled with R-Phycoerythrin (PE). This antibody has been tested by flow cytometry for binding to human CDH6 on CDH6 HEK293 Cell Line (BPS Bioscience #82540). FluoSite(TM) is a tag-based method for site-specific conjugation of antibodies with fluorophores, ensuring the labeling site is far from the antigen-binding domain to preserve antibody functionality. This precise, consistent labeling ensures the homogeneity of the labeled antibody preparation, making it ideal for flow cytometry and other high-sensitivity applications. Cadherin-6 (CDH6), also known as K-cadherin, belongs to the cadherin superfamily of cell adhesion molecules and is a single pass type 1 transmembrane protein. During development, CDH6 plays a role in neural crest morphogenesis and is important for central nervous system and kidney specification. CDH6 is expressed at high levels in tumor cells of diverse origin including thyroid, gastric, ovarian, and oral squamous cell cancer. CDH6 and other cadherin family members are promising immunotherapy targets for ADC (antibody drug conjugate) and CAR-T therapies due to their role at many stages of cancer progression including tumor initiation, growth, and metastasis.