Anti-ZNF541

function:Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis.,similarity:Contains 1 ELM2 domain.,similarity:Contains 1 SANT domain.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Interacts with HDAC1 and HSPA2., Protein function: Transcription regulator which is essential for male fertility and for the completion of meiotic prophase in spermatocytes. Regulates progression of the pachytene stage of meiotic prophase by activating the expression of genes involved in meiosis during spermatogenesis. Maintains the repression of pre-pachytene transcriptional programs, including meiotic double-strand breaks (DSB) formation genes in pachytene spermatocytes and suppresses aberrant DSB formation after mid-pachytene, thus ensuring meiosis progression. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Nucleus .