Anti-WTAP (IHC)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IHC-00368-T 10 µl (5+ slides) -

3 - 9 Werktage*

131,00 €
IHC-00368 100 µl (50+ slides) -

3 - 9 Werktage*

493,00 €
 
Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein... mehr
Produktinformationen "Anti-WTAP (IHC)"
Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). [The UniProt Consortium]
Schlagworte: Anti-WTAP, Anti-hFL(2)D, Anti-KIAA0105, Anti-WT1-associated protein, Anti-Female-lethal(2)D homolog, Anti-Pre-mRNA-splicing regulator WTAP, Anti-Wilms tumor 1-associating protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: IHC-00368

Eigenschaften

Anwendung: IHC, IHC-IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human (Erwartet: X. Laevis, X. Tropicalis, Bovine, Horse, Guinea Pig, Swine, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Tasmanian Devil, White-tufted-ear Marmoset, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by IHC-00368 maps to a region between residue 346 and 396 of human Wilms tumor 1 associated protein using the numbering given in entry NP_004897.2 (GeneID 9589).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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