Anti-TSSP

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008], Protein function: Protease that may play a role in T-cell development. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cytoplasmic vesicle. Vesicular, either lysosomal or endosomal.