Anti-TSC1

Anti-TSC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSC1 from other sources has not been determined. Protein function: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. [The UniProt Consortium]