Anti-TRPV2 (VRL1)

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transient Receptor Potential Cation Channel Subfamily V Member 2, also known as VRL1, is a protein that, in humans, is encoded by the TRPV2 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52oC. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat. Protein function: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius, is not activated by vanilloids and acidic pH. [The UniProt Consortium]