Anti-TRAF6 Binding Protein

Anti-TRAF6 Binding Protein Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with TRAF6 BP from human based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TRAF6BP from other sources has not been determined. Protein function: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. [The UniProt Consortium]