Anti-TPMT

Anti-TPMT
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-RQ4355 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Thiopurine methyltransferase or thiopurine... mehr
Produktinformationen "Anti-TPMT"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. Protein function: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. [The UniProt Consortium]
Schlagworte: Anti-TPMT, EC=2.1.1.67, Anti-Thiopurine methyltransferase, Anti-Thiopurine S-methyltransferase, TPMT Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: RQ4355

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: A recombinant human protein corresponding to amino acids M1-K245 was used as the immunogen for the TPMT antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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