Anti-TNFAIP8L3

caution:It is uncertain whether Met-1 or Met-89 is the initiator.,similarity:Belongs to the TNFAIP8 family., Protein function: Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000. Cellular localization: Cytoplasm . Cell membrane . On PDGF activation, translocates from cytoplasm to plasma membrane. .