Anti-TNFAIP8

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 93%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 54%, Pig - 99%, Cynomolgus monkey - 99%. IHC Verification: Fail (Tonsil). WB Verification: succeed. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification: -. Antigen ID: ABS-PP-1175. Core Sequence: VATDVFNSKN LAVQAQKKIL GKMVSKSIAT TLIDDTSSEV LDELYRVTRE YTQNKKEAEK IIKNLIKTVI KLAILYRNNQ. Recombinant Antibody: Protein Function: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation [The Uniprot Consortium]