Anti-TNF-a

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor Necrosis Factor alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, and apoptosis, and has been implicated in a variety of diseases, including autoimmune diseases and cancer. Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. [The UniProt Consortium]