Anti-TLR9, clone TR9541

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
ARG41718.50	50 µg		-	-	6 - 14 Werktage*		544,00 €

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Protein function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors)... mehr

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Produktinformationen "Anti-TLR9, clone TR9541"

Protein function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028). Controls lymphocyte response to Helicobacter infection. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366). [The UniProt Consortium]

Schlagworte:	Anti-TLR9, Anti-CD289, Anti-Toll-like receptor 9
Hersteller:	Arigo Biolaboratories
Hersteller-Nr:	ARG41718

Eigenschaften

Anwendung:	FC, IHC (paraffin), WB
Antikörper-Typ:	Monoclonal
Klon:	TR9541
Konjugat:	No
Wirt:	Mouse
Spezies-Reaktivität:	human, mouse
Immunogen:	Recombinant protein fragment around the N-terminal region of Human TLR9
MW:	116 kD
Format:	Purified