Anti-TLR4, clone MTS510

Anti-TLR4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR4 from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR4 from other sources has not been determined. Toll Like Receptors and signaling research. Protein function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [The UniProt Consortium]