Anti-TFPI

Anti-TFPI
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-FD4 100 µg - -

6 - 10 Werktage*

684,00 €
 
Anti-TFPI Antibody was affinity purified from monospecific antiserum by immunoaffinity... mehr
Produktinformationen "Anti-TFPI"
Anti-TFPI Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist, this antibody will detect both isoforms. Protein function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5- formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT. [The UniProt Consortium]
Schlagworte: Anti-TET2, Anti-KIAA1546, Anti-Nbla00191, Anti-Methylcytosine dioxygenase TET2
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-FD4

Eigenschaften

Anwendung: ELISA, IHC, IFM, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: 13 amino acid peptide near the N-terminus of human TFPI.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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