Anti-STAT2, clone 19G8.H2.H6

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
200-301-B65S	25 µl		-	-	6 - 10 Werktage*		180,00 €
200-301-B65	100 µg		-	-	6 - 10 Werktage*		698,00 €

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Protein function: Signal transducer and activator of transcription that mediates signaling by... mehr

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Produktinformationen "Anti-STAT2, clone 19G8.H2.H6"

Protein function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [The UniProt Consortium]

Schlagworte:	Anti-p113, Anti-STAT2, Anti-Signal transducer and activator of transcription 2
Hersteller:	Rockland Immunochemicals
Hersteller-Nr:	200-301-B65

Eigenschaften

Anwendung:	ELISA, IHC, WB
Antikörper-Typ:	Monoclonal
Klon:	19G8.H2.H6
Konjugat:	No
Wirt:	Mouse
Spezies-Reaktivität:	human (Erwartet: rat, mouse)
Immunogen:	synthetic peptide corresponding to residues near the C-terminus of mouse STAT2
Format:	Purified