Anti-SMOC1

This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. [The UniProt Consortium]