Anti-SMAD7

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA028897.25 25 µl -

7 - 10 Werktage*

330,00 €
ATA-HPA028897.100 100 µl -

7 - 10 Werktage*

463,00 €
 
Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1... mehr
Produktinformationen "Anti-SMAD7"
Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%
Schlagworte: Anti-SMAD7, Anti-MADH7, Anti-Smad7, Anti-hSMAD7, Anti-SMAD 7, Anti-MAD homolog 8, Anti-MAD homolog 7, Anti-SMAD family member 7, Anti-Mothers against DPP homolog 8, Anti-Mothers against DPP homolog 7, Anti-Mothers against decapentaplegic homolog 7
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA028897

Eigenschaften

Anwendung: IHC, ICC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EVKRLCCCES YGKINPELVC CNPHHLSRLC ELESPPPPYS RYPMDFLKPT ADCPDAVPSS AETGGTNYLA PGGLSDSQLL LEPGDRSHWC VVAYWEEKTR VGRLYCVQEP SLDIFYDLPQ GNG (ATA-APrEST86713)

Datenbank Information

KEGG ID : K19631 | Passende Produkte
UniProt ID : O15105 | Passende Produkte
Gene ID : GeneID 4092 | Passende Produkte
Protein Atlas Nr. : ENSG00000101665

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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