Anti-SMAD6

Anti-SMAD6
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
200-401-I15 100 µg - -

3 - 8 Werktage*

860,00 €
 
Anti-SMAD6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to... mehr
Produktinformationen "Anti-SMAD6"
Anti-SMAD6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD6 from Human, Mouse, New World monkey, Rat and Sheep based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-SMAD6 from other sources has not been determined. Protein function: Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [The UniProt Consortium]
Schlagworte: Anti-SMAD6, Anti-MADH6, Anti-Smad6, Anti-hSMAD6, Anti-SMAD 6, Anti-MAD homolog 6, Anti-SMAD family member 6, Anti-Mothers against DPP homolog 6, Anti-Mothers against decapentaplegic homolog 6
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 200-401-I15

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: peptide corresponding to two internal amino acid sequences in the human SMAD6 protein.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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