Anti-SLC11A1

SLC11A1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Rat and for use in ELISA, WB, IHC, IF applications. SLC11A1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes. [The UniProt Consortium]