Anti-SFMBT2, clone PCRP-SFMBT2-1B7

1 mg/ml in 1X PBS, BSA free, sodium azide free. The SFMBT2 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication. Protein function: Transcriptional repressor of HOXB13 gene. [The UniProt Consortium]